SCHEMBL533400

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL533115	0.81	BACE1 (0.37)	TSHRKDM4EKIF11
	SCHEMBL533992	0.81	TSHR (0.38)	TSHR
	SCHEMBL208143	0.74	CYP1A2 (0.44)	ALDH1A1HPGDHSD17B10TDP1NPC1
	SCHEMBL533224	0.73	SRD5A1 (0.37)	ALDH1A1HPGDHSD17B10KDM4EKIF11
	SCHEMBL4148062	0.69	ALDH1A1 (0.41)	ALDH1A1HPGDALOX15HSD17B10TDP1
	SCHEMBL17870639	0.69	CA12 (0.44)	ALDH1A1HPGDALOX15HSD17B10TDP1
	SCHEMBL207471	0.69	CYP2A6 (0.38)	ALDH1A1MEN1MAPTKMT2ACYP1A2
	SCHEMBL3418351	0.69	ALDH1A1 (0.48)	ALDH1A1HPGDALOX15HSD17B10TDP1
	SCHEMBL983124	0.69	ALDH1A1 (0.48)	ALDH1A1HPGDALOX15HSD17B10TDP1
	SCHEMBL29447635	0.69	ALDH1A1 (0.48)	ALDH1A1HPGDALOX15HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.