Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.48 |
| ▸ | ZAP70 | P43403 | 6/20 | 0.48 |
| ▸ | SYK | P43405 | 6/20 | 0.48 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311682 | 0.83 | CSNK2A2 (0.41) | SRCZAP70SYKCDK2CSNK2A2 | |
| SCHEMBL5331600 | 0.82 | EPAS1 (0.52) | SRCZAP70SYKCSNK2A2CSNK2B | |
| SCHEMBL5335403 | 0.78 | NPC1 (0.46) | SRCZAP70SYKCSNK2A2CSNK2B | |
| SCHEMBL5343088 | 0.76 | RAB9A (0.66) | SRCKDM4ECSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20278247 | 0.76 | HTR2C (0.41) | KDM4ECSNK2A2CSNK2BCSNK2A1MEN1 | |
| SCHEMBL2067775 | 0.76 | GRM4 (0.43) | CDK2KDM4EGRM4MEN1KMT2A | |
| SCHEMBL30737928 | 0.75 | GRM4 (0.42) | CSNK2A2CSNK2BCSNK2A1GRM4MEN1 | |
| SCHEMBL26928553 | 0.75 | GRM4 (0.42) | CSNK2A2CSNK2BCSNK2A1GRM4MEN1 | |
| Hydrochloric Acid SCHEMBL5332537 | 0.75 | NPC1 (0.43) | SRCZAP70SYKCSNK2A2CSNK2B | |
| SCHEMBL24795236 | 0.74 | KDM4E (0.41) | SRCZAP70SYKKDM4EKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | disclosed |