Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.42 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335403 | 0.92 | NPC1 (0.46) | EPAS1NPC1RAB9ASRCZAP70 | |
| SCHEMBL5343088 | 0.88 | RAB9A (0.66) | EPAS1NPC1RAB9ASRCMEN1 | |
| Hydrochloric Acid SCHEMBL5332537 | 0.88 | NPC1 (0.43) | EPAS1NPC1RAB9ASRCZAP70 | |
| SCHEMBL5334309 | 0.82 | SRC (0.48) | NPC1RAB9ASRCZAP70SYK | |
| SCHEMBL5314760 | 0.79 | MEN1 (0.57) | NPC1RAB9ASRCMEN1KMT2A | |
| SCHEMBL5311682 | 0.78 | CSNK2A2 (0.41) | RAB9ASRCZAP70SYKMEN1 | |
| Hydrochloric Acid SCHEMBL5369271 | 0.78 | MEN1 (0.56) | NPC1SRCMEN1KMT2ACSNK2A1 | |
| SCHEMBL5378756 | 0.78 | MEN1 (0.47) | NPC1RAB9ASRCMEN1KMT2A | |
| SCHEMBL5315096 | 0.78 | RAB9A (0.79) | NPC1RAB9AMEN1KMT2AEGFR | |
| SCHEMBL5334156 | 0.76 | MEN1 (0.46) | NPC1RAB9AMEN1KMT2ACSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |