Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332439 | 0.93 | SYK (0.42) | SYKCHRNA7ALDH1A1KDM4EABCB1 | |
| SCHEMBL5339851 | 0.90 | KDM4E (0.39) | SYKCHRNA7ALDH1A1KDM4EMAPT | |
| SCHEMBL16156465 | 0.87 | KDM4E (0.43) | CHRNA7ALDH1A1KDM4EMAPT | |
| SCHEMBL14436096 | 0.85 | SYK (0.42) | SYKCHRNA7ALDH1A1KDM4EABCB1 | |
| SCHEMBL16156471 | 0.83 | HSD17B10 (0.45) | SYKCHRNA7ALDH1A1KDM4EMAPT | |
| SCHEMBL5340379 | 0.81 | KDM4E (0.44) | ALDH1A1KDM4EMAPTRECQL | |
| SCHEMBL5335547 | 0.79 | PTPN1 (0.41) | CHRNA7ALDH1A1MAPTTDP1 | |
| SCHEMBL5334048 | 0.78 | KDM4E (0.45) | SYKALDH1A1KDM4EMAPT | |
| SCHEMBL16156467 | 0.77 | TOP2A (0.49) | ALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL5332563 | 0.75 | KDM4E (0.45) | SYKALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |