Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30414713 | 0.89 | L3MBTL1 (0.52) | KDM4EL3MBTL1HPGDALDH1A1HSD17B10 | |
| SCHEMBL5334625 | 0.89 | L3MBTL1 (0.52) | KDM4EL3MBTL1HPGDALDH1A1HSD17B10 | |
| SCHEMBL5334048 | 0.86 | KDM4E (0.45) | KDM4EL3MBTL1HPGDALDH1A1HSD17B10 | |
| SCHEMBL5339851 | 0.85 | KDM4E (0.39) | KDM4EL3MBTL1HPGDALDH1A1HSD17B10 | |
| SCHEMBL14436660 | 0.81 | L3MBTL1 (0.57) | KDM4EL3MBTL1HPGDALDH1A1HSD17B10 | |
| SCHEMBL5339446 | 0.79 | L3MBTL1 (0.49) | KDM4EL3MBTL1HPGDALDH1A1HSD17B10 | |
| SCHEMBL5334323 | 0.75 | SYK (0.45) | KDM4EALDH1A1MAPTSYK | |
| SCHEMBL5332439 | 0.72 | SYK (0.42) | KDM4EALDH1A1MAPTSYK | |
| SCHEMBL14436096 | 0.71 | SYK (0.42) | KDM4EALDH1A1GAAMAPTSYK | |
| SCHEMBL13523024 | 0.70 | KDM6B (0.68) | KDM4EHPGDALDH1A1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |