Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.35 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | UTRN | P46939 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5339562 | 0.83 | SMN1; SMN2 (0.40) | PTPN1PPARGPPARACEPT1ALDH1A1 | |
| SCHEMBL5332439 | 0.83 | SYK (0.42) | ALDH1A1CHRNA7MAPT | |
| SCHEMBL5337672 | 0.81 | PTPN1 (0.43) | PTPN1CEPT1ALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL5334323 | 0.79 | SYK (0.45) | ALDH1A1CHRNA7MAPTTDP1 | |
| SCHEMBL5339851 | 0.78 | KDM4E (0.39) | ALDH1A1CHRNA7MAPTSMN1; SMN2 | |
| SCHEMBL14436096 | 0.75 | SYK (0.42) | ALDH1A1CHRNA7MAPTTDP1 | |
| SCHEMBL16156465 | 0.75 | KDM4E (0.43) | ALDH1A1CHRNA7MAPTSMN1; SMN2F2RL3 | |
| SCHEMBL5332553 | 0.75 | CEPT1 (0.51) | PTPN1CEPT1ALDH1A1CHRNB4CHRNA3 | |
| SCHEMBL14436666 | 0.72 | KDM4E (0.41) | ALDH1A1CHRNA7MAPTSMN1; SMN2TDP1 | |
| SCHEMBL16156467 | 0.72 | TOP2A (0.49) | ALDH1A1MAPTSMN1; SMN2LIN28ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |