SCHEMBL5334368

SCHEMBL5334368

Nc1c(C=O)cccc1-c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 2/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
ALDH1A1 P00352 2/20 0.45
HSD17B10 Q99714 1/20 0.45
MAPT P10636 1/20 0.43
GRIN2D O15399 2/20 0.40
GRIN3B O60391 2/20 0.40
GRIN1 Q05586 2/20 0.40
GRIN2A Q12879 2/20 0.40
GRIN2B Q13224 2/20 0.40
GRIN2C Q14957 2/20 0.40
GRIN3A Q8TCU5 2/20 0.40
XDH P47989 1/20 0.39
TSHR P16473 1/20 0.39
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28245023 0.84 MAPT (0.43) KMT2ALMNAMEN1THRBBLM
SCHEMBL28033470 0.83 MEN1 (0.37) KMT2ALMNAMEN1THRBBLM
SCHEMBL4751561 0.83 ALDH1A1 (0.39) KMT2ALMNAMEN1THRBBLM
SCHEMBL27874489 0.82 HRH3 (0.43) KMT2ALMNAMEN1THRBBLM
SCHEMBL5711323 0.81 LMNA (0.57) KMT2ALMNAMEN1THRBBLM
SCHEMBL96494 0.81 LMNA (0.57) KMT2ALMNAMEN1THRBBLM
Benzene SCHEMBL27923728 0.81 LMNA (0.57) KMT2ALMNAMEN1THRBBLM
SCHEMBL28150009 0.80 ALDH1A1 (0.45) LMNAALDH1A1HSD17B10MAPTGRIN2D
SCHEMBL7394892 0.79 ALDH1A1 (0.41) ALDH1A1HSD17B10MAPTGRIN2DGRIN3B
SCHEMBL29012812 0.79 ALDH1A1 (0.49) KMT2ALMNAMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110024192-A Energy storage device priming coat and energy storage device electrode primary coat foil 日产化学株式会社 2019-07-16 CN disclosed
CN-109997264-A Film containing carbon nanotube 日产化学株式会社 2019-07-09 CN disclosed
CN-107615536-A Primary coat paper tinsel for energy storage device electrode 日产化学工业株式会社 2018-01-19 CN disclosed
CN-105670608-B High-selectivity fluorescent probe capable of detecting nickel ions in mitochondria of living cells and preparation method thereof 安徽大学 2017-09-26 CN disclosed
CN-101481609-A Symmetrical multiphoton pump luminescent material and preparation thereof UNIV SOUTHEAST (CN) 2009-07-15 CN disclosed
WO-2007081091-A1 RHODANDSE DERIVARIVES, A PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2007-07-19 WO disclosed
CN-1610547-A N-(2-arylethyl)benzylamines as antagonists of the 5-HT6 receptor LILLY CO ELI (US) 2005-04-27 CN disclosed
US-4556667-A (2-((AMINOPYRIDINYL)AMINO)PHENYL)ARYLMETHANONE INTERMEDIATES A. H. ROBINS COMPANY, INCORPORATED (US) 1985-12-03 US disclosed