Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 13/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337346 | 0.87 | TAS2R14 (0.52) | TAS2R14TP53LMNAMAPK1 | |
| SCHEMBL3860348 | 0.87 | TAS2R14 (0.63) | TAS2R14TP53LMNAMAPK1 | |
| SCHEMBL3853015 | 0.80 | TAS2R14 (0.72) | TAS2R14TP53LMNAMAPK1GAA | |
| SCHEMBL3853063 | 0.78 | TAS2R14 (0.76) | TAS2R14TP53LMNAMAPK1 | |
| SCHEMBL3859841 | 0.77 | TAS2R14 (0.58) | TAS2R14TP53LMNA | |
| SCHEMBL3856963 | 0.76 | TAS2R14 (0.66) | TAS2R14TP53LMNAMAPK1 | |
| SCHEMBL13714179 | 0.75 | TAS2R14 (0.59) | TAS2R14TP53 | |
| SCHEMBL3856062 | 0.75 | TAS2R14 (0.70) | TAS2R14TP53LMNAMAPK1 | |
| SCHEMBL3860040 | 0.74 | TAS2R14 (0.63) | TAS2R14LMNAMAPK1 | |
| SCHEMBL3851892 | 0.74 | TAS2R14 (0.60) | TAS2R14CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067817-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2007-06-14 | — | — | WO | claimed |