Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 13/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334429 | 0.87 | TAS2R14 (0.55) | TAS2R14MAPK1LMNATP53 | |
| SCHEMBL13714165 | 0.86 | TAS2R14 (0.59) | TAS2R14MAPK1SMN1; SMN2 | |
| SCHEMBL3851328 | 0.86 | TAS2R14 (0.59) | TAS2R14MAPK1SMN1; SMN2 | |
| SCHEMBL5315438 | 0.80 | TAS2R14 (0.56) | TAS2R14MAPK1SMN1; SMN2LMNA | |
| SCHEMBL3856007 | 0.79 | MAPK1 (0.52) | TAS2R14MAPK1SMN1; SMN2LMNA | |
| SCHEMBL13714179 | 0.78 | TAS2R14 (0.59) | TAS2R14TP53 | |
| SCHEMBL3853015 | 0.77 | TAS2R14 (0.72) | TAS2R14MAPK1LMNATP53 | |
| SCHEMBL3858876 | 0.76 | TAS2R14 (0.55) | TAS2R14STAT3 | |
| SCHEMBL3853063 | 0.75 | TAS2R14 (0.76) | TAS2R14MAPK1LMNATP53 | |
| SCHEMBL3856963 | 0.75 | TAS2R14 (0.66) | TAS2R14MAPK1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007067817-A1 | ABCA1 ELEVATING COMPOUNDS | CV THERAPEUTICS, INC. (US) | 2007-06-14 | — | — | WO | claimed |