Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5338579 | 0.76 | KDM4E (0.58) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL5451976 | 0.72 | KDM4E (0.54) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL11639254 | 0.70 | TDP1 (0.54) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL18095730 | 0.69 | ALDH1A1 (0.59) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL21902359 | 0.68 | KDM4E (0.59) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL12072279 | 0.68 | KDM4E (0.55) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL19128191 | 0.67 | KDM4E (0.53) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL11089239 | 0.67 | ALDH1A1 (0.59) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL620812 | 0.67 | KDM4E (0.57) | KDM4EMEN1KMT2ATDP1HTT | |
| SCHEMBL22031968 | 0.66 | KMT2A (0.45) | KDM4EMEN1KMT2ATDP1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157408-B2 | 5,7-Dibromo-8-(2-hydroxyethyl) quinoline and 5,7-dibromo-8-(2-methoxycarbonyloxyethyl) quinoline, for treating plant diseases | VALENT BIOSCIENCES CORPORATION (US) | 2007-01-02 | — | — | US | claimed |
| WO-2005060748-A1 | FUNGICIDE | VALENT BIOSCIENCES CORPORATION (US) | 2005-07-07 | — | — | WO | claimed |
| US-20050131013-A1 | Fungicide | VALENT BIOSCIENCES CORPORATION | 2005-06-16 | — | — | US | claimed |
| US-7157408-B2 | 5,7-Dibromo-8-(2-hydroxyethyl) quinoline and 5,7-dibromo-8-(2-methoxycarbonyloxyethyl) quinoline, for treating plant diseases | VALENT BIOSCIENCES CORPORATION (US) | 2007-01-02 | — | — | US | disclosed |
| US-7157408-B2 | 5,7-Dibromo-8-(2-hydroxyethyl) quinoline and 5,7-dibromo-8-(2-methoxycarbonyloxyethyl) quinoline, for treating plant diseases | VALENT BIOSCIENCES CORPORATION (US) | 2007-01-02 | — | — | US | disclosed |
| WO-2005060748-A1 | FUNGICIDE | VALENT BIOSCIENCES CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |
| WO-2005060748-A1 | FUNGICIDE | VALENT BIOSCIENCES CORPORATION (US) | 2005-07-07 | — | — | WO | disclosed |
| US-20050131013-A1 | Fungicide | VALENT BIOSCIENCES CORPORATION | 2005-06-16 | — | — | US | disclosed |
| US-20050131013-A1 | Fungicide | VALENT BIOSCIENCES CORPORATION | 2005-06-16 | — | — | US | disclosed |