SCHEMBL5335059

SCHEMBL5335059

Cc1ccc(S(=O)(=O)C(C)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.52
CA1 P00915 3/20 0.48
CA2 P00918 3/20 0.48
MMP2 P08253 2/20 0.48
MMP1 P03956 1/20 0.48
MMP9 P14780 1/20 0.48
MMP8 P22894 1/20 0.48
MMP13 P45452 1/20 0.48
CA12 O43570 3/20 0.48
CA9 Q16790 3/20 0.48
CA3 P07451 1/20 0.48
CA6 P23280 1/20 0.48
CA5A P35218 1/20 0.48
CA7 P43166 1/20 0.48
CA5B Q9Y2D0 1/20 0.48
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TLR9 Q9NR96 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30121315 0.84 GAA (0.54) GAACA1CA2MMP2MMP1
SCHEMBL25678915 0.83 GAA (0.48) GAACA1CA2MMP2MMP1
SCHEMBL178444 0.81 GAA (0.56) GAACA1CA2MMP2MMP1
SCHEMBL1149214 0.81 GAA (0.56) GAACA1CA2MMP2MMP1
SCHEMBL30896660 0.81 GAA (0.56) GAACA1CA2MMP2MMP1
SCHEMBL15827085 0.80 GAA (0.50) GAACA1CA2MMP2MMP1
SCHEMBL8959293 0.80 GAA (0.50) GAACA1CA2MMP2MMP1
SCHEMBL7758469 0.80 TSHR (0.52) GAACA1CA2MMP2MMP1
SCHEMBL9646612 0.80 MMP13 (0.34) CA1CA2MMP2MMP1MMP13
SCHEMBL27339160 0.80 GAA (0.50) GAACA1CA2MMP2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US claimed
US-4053373-A ELECTROPLATING OF NICKEL, COBALT, NICKEL-COBALT, NICKEL-IRON, COBALT-IRON AND NICKEL-IRON-COBALT DEPOSITS M & T CHEMICALS INC. (US) 1977-10-11 US claimed
CN-105452344-A Polydendrons UNIV LIVERPOOL 2016-03-30 CN disclosed
CN-105451772-A Polydendrons UNIV LIVERPOOL 2016-03-30 CN disclosed
US-7777033-B2 Monomer with anti-microbial character, polymer using the same, and manufacturing method thereof MICRO SCIENCE TECH CO., LTD. (KR) 2010-08-17 US disclosed
US-7572301-B2 Fibre-reactive dyes, their preparation and their use HUNTSMAN INTERNATIONAL LLC (US) 2009-08-11 US disclosed
US-20080250575-A1 Fibre-Reactive Dyes, Their Preparation And Their Use HUNTSMAN INTERNATIONAL LLC 2008-10-16 US disclosed
US-7294716-B2 Process for preparing isomerically pure prodrugs of proton pump inhibitors ALLERGAN, INC. (US) 2007-11-13 US disclosed
WO-2007064291-A1 METHOD AND COMPOUNDS FOR RNA SYNTHESIS CHATTOPADHYAYA JYOTI (SE) 2007-06-07 WO disclosed
EP-1556371-B1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS PRODRUGS OF PROTON PUMP INHIBITOR WINSTON PHARMACEUTICALS LLC (US) 2006-04-19 EP disclosed
EP-1644352-A1 PROCESS FOR PREPARING ISOMERICALLY PURE PRODRUGS OF PROTON PUMP INHIBITORS Allergan, Inc. (US) 2006-04-12 EP disclosed
EP-0602914-A1 Ink compositions for ink jet printing XEROX CORPORATION (US) 1994-06-22 EP disclosed
US-5300143-A Water soluble dye, sulfone, and amide or cyclic amine XEROX CORPORATION (US) 1994-04-05 US disclosed
EP-0305845-B1 PYRIDYL ETHANOL AMINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESSES FOR THEIR PREPARATION Dr. Karl Thomae GmbH (DE) 1992-10-28 EP disclosed
EP-0305845-A1 Pyridyl ethanol amines, pharmaceutical compositions containing them and processes for their preparation Dr. Karl Thomae GmbH (DE) 1989-03-08 EP disclosed
EP-0115054-B1 BETA-ELIMINATING POLYMERS FOR DIFFUSION CONTROL IN PHOTOGRAPHIC PRODUCTS POLAROID CORPORATION (US) 1988-02-10 EP disclosed
EP-0163996-A1 2,2-Dimethyl-3-formylcyclopropanes and process for their preparation BAYER AG (DE) 1985-12-11 EP disclosed
US-4522996-A ACRYLIC ESTER CARBAMATE CONTAINING LABILE PROTON POLAROID CORPORATION (US) 1985-06-11 US disclosed
EP-0115054-A2 Beta-eliminating polymers for diffusion control in photographic products POLAROID CORPORATION (US) 1984-08-08 EP disclosed
US-4458001-A HOLD-RELEASE LAYERS POLAROID CORPORATION (US) 1984-07-03 US disclosed