Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265309 | 0.88 | ALDH1A1 (0.51) | L3MBTL1NPSR1MEN1KMT2AGPR55 | |
| SCHEMBL4192118 | 0.87 | ALDH1A1 (0.57) | L3MBTL1NPSR1MEN1KMT2AGPR55 | |
| SCHEMBL5262192 | 0.87 | TUBB4A (0.46) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL5263050 | 0.87 | ALDH1A1 (0.43) | L3MBTL1NPSR1MEN1KMT2AGPR55 | |
| SCHEMBL5264429 | 0.85 | SMN1; SMN2 (0.53) | L3MBTL1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL13853225 | 0.84 | TUBB4A (0.49) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL5261790 | 0.82 | MDM2 (0.41) | L3MBTL1NPSR1GPR55MDM2ALDH1A1 | |
| SCHEMBL5260549 | 0.82 | ALDH1A1 (0.47) | L3MBTL1NPSR1MEN1KMT2AGPR55 | |
| SCHEMBL13853224 | 0.80 | CSNK1D (0.41) | RAB9AKDM4EDHODHPTGS2 | |
| SCHEMBL28509330 | 0.78 | MDM2 (0.60) | L3MBTL1NPSR1MEN1KMT2AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824828-A2 | PYRIDINE BASED COMPOUNDS USEFUL AS INTERMEDIATES FOR PHARMACEUTICAL OR AGRICULTURAL END-PRODUCTS | Peakdale Molecular Limited (GB) | 2007-08-29 | — | — | EP | claimed |
| WO-2006059103-A2 | PYRIDINE BASED COMPOUNDS USEFUL AS INTERMEDIATES FOR PHARMACEUTICAL OR AGRICULTURAL END-PRODUCTS | PEAKDALE MOLECULAR LIMITED (GB) | 2006-06-08 | — | — | WO | claimed |