Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 9/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.35 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.35 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5344186 | 0.91 | F9 (0.41) | CNR1CNR2KDM4EMAPTTDP1 | |
| SCHEMBL5344423 | 0.90 | PTPN1 (0.48) | PTPN1CNR1CNR2PPARDNCEH1 | |
| SCHEMBL6580117 | 0.81 | PTPN1 (0.46) | PTPN1CNR1CNR2KDM4EMAPT | |
| SCHEMBL5341879 | 0.80 | F9 (0.41) | PTPN1CNR1CNR2KDM4EMAPT | |
| SCHEMBL5342448 | 0.78 | PTPN1 (0.38) | PTPN1CNR1CNR2MAPTATM | |
| SCHEMBL5338631 | 0.76 | PTPN1 (0.46) | PTPN1CNR1CNR2PPARDCTSD | |
| SCHEMBL5343854 | 0.76 | PTPN1 (0.47) | PTPN1PPARDMAPT | |
| SCHEMBL5337133 | 0.73 | PTPN1 (0.35) | PTPN1CNR1CNR2MAPTATM | |
| SCHEMBL5343856 | 0.73 | PTPN1 (0.45) | PTPN1CNR1CNR2PPARDPTGDR2 | |
| SCHEMBL6583844 | 0.72 | KDM4E (0.43) | PTPN1KDM4EMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163954-B2 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2007-01-16 | — | — | US | claimed |
| EP-1664015-A1 | SUBSTITUTED NAPHTHYL BENZOTHIOPHENE ACIDS | Wyeth (US) | 2006-06-07 | — | — | EP | claimed |
| WO-2005030750-A1 | SUBSTITUTED NAPHTHYL BENZOTHIOPHENE ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | claimed |
| US-20050070587-A1 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2005-03-31 | — | — | US | claimed |
| US-7163954-B2 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2007-01-16 | — | — | US | disclosed |
| EP-1664015-A1 | SUBSTITUTED NAPHTHYL BENZOTHIOPHENE ACIDS | Wyeth (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005030750-A1 | SUBSTITUTED NAPHTHYL BENZOTHIOPHENE ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070587-A1 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070587-A1 | Substituted naphthyl benzothiophene acids | TST, GNPAT, NUDT1 | PTPN1 1717/4885CNR1 4226/4885CNR2 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.