Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3717672 | 0.80 | SCN5A (0.41) | SCN5AMAPTALDH1A1TSHRPDE4A | |
| SCHEMBL18152141 | 0.78 | SCN5A (0.46) | SCN5AESR1MAPTMEN1KMT2A | |
| SCHEMBL12476303 | 0.76 | ESR1 (0.47) | SCN5AESR1MAPTMEN1KMT2A | |
| SCHEMBL25328087 | 0.76 | IDO1 (0.38) | SCN5AESR1MAPTMEN1KMT2A | |
| SCHEMBL15012498 | 0.73 | TUBB1 (0.38) | ESR1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7737634 | 0.73 | ALDH1A1 (0.38) | SCN5AESR1ALDH1A1TSHRKDM4E | |
| SCHEMBL16959326 | 0.72 | SCN4A (0.44) | SCN5AMAPTMEN1KMT2AGABRP | |
| SCHEMBL25330137 | 0.72 | ESR1 (0.35) | SCN5AESR1MAPTMEN1KMT2A | |
| SCHEMBL1608280 | 0.72 | MAPT (0.33) | MAPTMEN1KMT2AGABRPGABRD | |
| SCHEMBL24403598 | 0.71 | ALDH1A1 (0.37) | MAPTMEN1KMT2AGABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778142-B | Preparation method of bisoprolol free base | 北京金城泰尔制药有限公司沧州分公司 | 2023-03-28 | — | — | CN | claimed |
| CN-112778142-A | Preparation method of bisoprolol free base | 北京金城泰尔制药有限公司沧州分公司 | 2021-05-11 | — | — | CN | claimed |
| CN-102557891-A | Preparation method for 4-isopropoxy ethyoxyl methyl phenol | JINAN INOVAS CHEMICAL CO LTD | 2012-07-11 | — | — | CN | claimed |
| CN-115974802-A | Preparation method of bisoprolol fumarate intermediate | 黑龙江珍宝岛药业股份有限公司鸡西分公司 | 2023-04-18 | — | — | CN | disclosed |
| CN-112778142-B | Preparation method of bisoprolol free base | 北京金城泰尔制药有限公司沧州分公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-112778142-B | Preparation method of bisoprolol free base | 北京金城泰尔制药有限公司沧州分公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-112778142-A | Preparation method of bisoprolol free base | 北京金城泰尔制药有限公司沧州分公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-112778142-A | Preparation method of bisoprolol free base | 北京金城泰尔制药有限公司沧州分公司 | 2021-05-11 | — | — | CN | disclosed |
| CN-112194587-A | Preparation method of chiral bisoprolol fumarate | 江苏悦兴医药技术有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-112194587-A | Preparation method of chiral bisoprolol fumarate | 江苏悦兴医药技术有限公司 | 2021-01-08 | — | — | CN | disclosed |
| CN-102557891-A | Preparation method for 4-isopropoxy ethyoxyl methyl phenol | JINAN INOVAS CHEMICAL CO LTD | 2012-07-11 | — | — | CN | disclosed |
| WO-2007069266-A2 | A NOVEL PROCESS FOR THE SYNTHESIS OF BISODPROLOL AND ITS INTERMEDIATE | UNICHEM LABORATORIES LIMITED (IN) | 2007-06-21 | — | — | WO | disclosed |