Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062080 | 0.87 | SCN5A (0.43) | SCN5AESR1ALDH1A1KDM4EHPGD | |
| SCHEMBL11131743 | 0.85 | NQO1 (0.46) | ESR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8940830 | 0.84 | ESR1 (0.42) | SCN5AESR1ALDH1A1KDM4EHPGD | |
| SCHEMBL10481651 | 0.81 | TYR (0.44) | SCN5AESR1ESR2LTA4HCA12 | |
| SCHEMBL12476303 | 0.80 | ESR1 (0.47) | SCN5AESR1ALDH1A1KDM4EHPGD | |
| SCHEMBL29633624 | 0.79 | CYP3A4 (0.43) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL17644154 | 0.79 | HSD17B10 (0.42) | ALDH1A1KDM4EHPGDHSD17B10GAA | |
| SCHEMBL5336040 | 0.78 | SCN5A (0.44) | SCN5AESR1ALDH1A1KDM4EHPGD | |
| SCHEMBL28035916 | 0.78 | GAA (0.42) | SCN5AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11883052 | 0.77 | TUBB1 (0.42) | ESR1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9980893-B2 | Dye composition comprising a 1,2,3,4-tetrahydropyrido[2,3-b]pyrazin-7-amine compound | L'OREAL (FR) | 2018-05-29 | — | — | US | disclosed |
| US-20160303018-A1 | DYE COMPOSITION COMPRISING A 1,2,3,4-TETRAHYDROPYRIDO[2,3-B]PYRAZIN-7-AMINE COMPOUND | L'OREAL (FR) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160303018-A1 | DYE COMPOSITION COMPRISING A 1,2,3,4-TETRAHYDROPYRIDO[2,3-B]PYRAZIN-7-AMINE COMPOUND | CBR3, AOC3, NOX3 | SCN5A 693/4885ESR1 2508/4885ALDH1A1 1378/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.