Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.37 |
| ▸ | NPC1 | O15118 | 8/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | TP53 | P04637 | 6/20 | 0.37 |
| ▸ | USP2 | O75604 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1169950 | 0.80 | MAPT (0.43) | MAPTPOLBGFERALDH1A1HSD17B10 | |
| SCHEMBL12775290 | 0.64 | MAPT (0.34) | MAPTPOLBGFERALDH1A1HSD17B10 | |
| SCHEMBL3436480 | 0.63 | TP53 (0.64) | MAPTPOLBGFERALDH1A1HSD17B10 | |
| SCHEMBL1749459 | 0.61 | MAPK1 (0.50) | MAPTPOLBALDH1A1HSD17B10NPC1 | |
| SCHEMBL13824168 | 0.60 | HSD17B10 (0.56) | MAPTPOLBALDH1A1HSD17B10NPC1 | |
| SCHEMBL13672438 | 0.60 | MAPK1 (0.39) | MAPTPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL1750234 | 0.60 | MAPT (0.45) | MAPTPOLBALDH1A1HSD17B10NPC1 | |
| SCHEMBL13824130 | 0.60 | ALDH1A1 (0.44) | MAPTPOLBALDH1A1HSD17B10NPC1 | |
| SCHEMBL1169614 | 0.59 | MAP3K12 (0.34) | ERCC1FEN1ERCC4 | |
| SCHEMBL874433 | 0.59 | L3MBTL1 (0.43) | MAPTPOLBALDH1A1HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007059125-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-05-24 | — | — | WO | disclosed |