SCHEMBL533613

SCHEMBL533613

COc1ccc2c(c1)c1ccccc1n2-c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.68
ALDH1A1 P00352 6/20 0.68
HPGD P15428 6/20 0.68
MAPT P10636 5/20 0.68
MEN1 O00255 5/20 0.68
KMT2A Q03164 5/20 0.68
HTT P42858 3/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
HSD17B10 Q99714 2/20 0.68
ATM Q13315 1/20 0.60
HTR6 P50406 2/20 0.50
FGFR1 P11362 1/20 0.48
EDNRA P25101 2/20 0.46
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
MAPK1 P28482 1/20 0.44
MAPK10 P53779 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19368319 0.95 KDM4E (0.64) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL28988538 0.93 MAPT (0.68) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL30352484 0.93 MAPT (0.68) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL16171589 0.93 KDM4E (0.59) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL14407598 0.92 MAPT (0.70) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL17694120 0.91 KDM4E (0.60) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL17694116 0.90 KDM4E (0.56) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL16171612 0.90 KDM4E (0.56) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL16171498 0.90 KDM4E (0.56) KDM4EALDH1A1HPGDMAPTMEN1
SCHEMBL25613235 0.90 KDM4E (0.60) KDM4EALDH1A1HPGDMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
WO-2023098740-A1 ORGANIC ROOM-TEMPERATURE ELECTROPHOSPHORESCENT MATERIAL, AND PREPARATION METHOD THEREFOR AND ORGANIC ELECTROLUMINESCENT DIODE THEREOF 云南大学 2023-06-08 WO disclosed
EP-2772483-B1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME TOSOH CORP (JP) 2017-03-29 EP disclosed
EP-2416392-B1 Light emitting device and display unit RICOH CO LTD (JP) 2016-05-25 EP disclosed
US-9263682-B2 Light emitting device and display unit RICOH COMPANY, LTD. (JP) 2016-02-16 US disclosed
US-9206202-B2 Carbazole derivative and semiconductor nanocrystal RICOH COMPANY, LTD. (JP) 2015-12-08 US disclosed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP disclosed
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL RICOH COMPANY, LTD. (JP) 2013-01-31 US disclosed
US-20120032115-A1 LIGHT EMITTING DEVICE AND DISPLAY UNIT RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
EP-2416392-A2 Light emitting device and display unit Ricoh Company, Ltd. (JP) 2012-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL NAT1, AHR, ARSA KDM4E 3482/4885ALDH1A1 1072/4885HPGD 3275/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS KDM4E 3740/4885ALDH1A1 2839/4885HPGD 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.