Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043978 | 0.81 | ATM (0.74) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL6050119 | 0.81 | ATM (0.67) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL6043670 | 0.80 | ATM (0.48) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL27155224 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL8149192 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL6042389 | 0.79 | ATM (0.71) | MEN1KMT2ATDP1ALDH1A1HPGD | |
| SCHEMBL5465893 | 0.77 | GNAI3 (0.67) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL9433090 | 0.76 | ATM (0.48) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL5536314 | 0.76 | ATM (0.48) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL294529 | 0.76 | GLA (0.59) | LMNAALDH1A1KDM4EUSP2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045962-A2 | NOVEL HDAC INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-04-26 | — | — | WO | disclosed |