Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 1/20 | 0.37 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233311 | 0.80 | HTR2C (0.42) | PIP4K2APIP4K2CKMT2ACHEK1AURKA | |
| SCHEMBL11202541 | 0.80 | ADORA2A (0.47) | PIP4K2APIP4K2CKMT2ACHEK1AURKA | |
| SCHEMBL5313613 | 0.73 | MAPK1 (0.51) | KMT2ACHEK1AURKADAPK3JAK2 | |
| SCHEMBL5461465 | 0.72 | CHEK1 (0.39) | KMT2ACHEK1AURKADAPK3JAK2 | |
| SCHEMBL23599714 | 0.69 | CYP2D6 (0.38) | KMT2ACHEK1AURKADAPK3JAK2 | |
| SCHEMBL3227643 | 0.69 | PIP4K2A (0.35) | PIP4K2APIP4K2CKMT2ANTRK1NTRK2 | |
| SCHEMBL18701492 | 0.69 | ADORA2A (0.36) | KMT2ACHEK1AURKADAPK3JAK2 | |
| SCHEMBL10244405 | 0.67 | NTRK1 (0.42) | PIP4K2APIP4K2CKMT2ACHEK1AURKA | |
| SCHEMBL13313242 | 0.67 | PARP1 (0.44) | KMT2AALDH1A1KDM4ECYP2D6CYP2C19 | |
| SCHEMBL29720445 | 0.66 | MAPT (0.46) | KMT2AALDH1A1SMN1; SMN2KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056214-A2 | N-ALKYL-N-ARYL-THIENOPYRIMIDIN-R-AMINES AND USES THEREOF | CYTOVIA, INC (US) | 2007-05-18 | — | — | WO | disclosed |