Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | IAPP | P10997 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336696 | 1.00 | ABCB1 (0.49) | ABCB1ALDH1A1SMN1; SMN2GLATDP1 | |
| SCHEMBL18073447 | 0.83 | ALDH1A1 (0.61) | ABCB1ALDH1A1SMN1; SMN2GLATDP1 | |
| SCHEMBL2910879 | 0.83 | ALDH1A1 (0.61) | ABCB1ALDH1A1SMN1; SMN2GLATDP1 | |
| SCHEMBL2910883 | 0.83 | ALDH1A1 (0.61) | ABCB1ALDH1A1SMN1; SMN2GLATDP1 | |
| SCHEMBL28652551 | 0.81 | ABCB1 (0.47) | ABCB1ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL13947423 | 0.81 | ABCB1 (0.47) | ABCB1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL28652549 | 0.81 | ABCB1 (0.47) | ABCB1ALDH1A1SMN1; SMN2MAPTGAA | |
| SCHEMBL11506011 | 0.80 | HSD17B3 (0.38) | ABCB1ALDH1A1SMN1; SMN2GLATDP1 | |
| SCHEMBL11506013 | 0.80 | HSD17B3 (0.38) | ABCB1ALDH1A1SMN1; SMN2GLATDP1 | |
| SCHEMBL5478309 | 0.78 | GLA (0.52) | ABCB1ALDH1A1SMN1; SMN2GLATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214151-A | Method for the preparation of α, β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1993-05-25 | — | — | US | claimed |
| US-20070112015-A1 | Substituted dihydropyridines and methods of use | CHEMOCENTRYX, INC. (US) | 2007-05-17 | — | — | US | disclosed |
| US-20070112015-A1 | Substituted dihydropyridines and methods of use | CHEMOCENTRYX, INC. (US) | 2007-05-17 | — | — | US | disclosed |
| US-20070112015-A1 | Substituted dihydropyridines and methods of use | CHEMOCENTRYX, INC. (US) | 2007-05-17 | — | — | US | disclosed |
| WO-2007051062-A2 | SUBSTITUTED DIHYDROPYRIDINES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| WO-2007051062-A2 | SUBSTITUTED DIHYDROPYRIDINES AND METHODS OF USE | CHEMOCENTRYX, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| US-5214151-A | Method for the preparation of α, β-unsaturated ketones | NIPPON SODA CO., LTD. (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0457912-A1 | METHOD FOR THE PREPARATION OF $g(a),$g(b)-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| WO-1991007371-A1 | METHOD FOR THE PREPARATION OF α,β-UNSATURATED KETONES | NIPPON SODA CO., LTD. (JP) | 1991-05-30 | — | — | WO | disclosed |
| EP-0133349-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1988-09-21 | — | — | EP | disclosed |
| US-4767879-A | PHENYL CYCLOHEXANE-1,3 DIONE DERIVATIVES; POSTEMERGENCE AND PREEMERGENCE HERBICIDES; PLANT GROWTH REGULATORS | ICI AUSTRALIA LIMITED (AU) | 1988-08-30 | — | — | US | disclosed |
| EP-0080301-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1988-08-24 | — | — | EP | disclosed |
| US-4760192-A | Herbicidal cyclohexane-1,3-dione derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-26 | — | — | US | disclosed |
| US-4717418-A | CEREAL SELECTIVE HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1988-01-05 | — | — | US | disclosed |
| US-4666510-A | Cyclohexenone derivatives and their herbicidal use. | ICI AUSTRALIA LIMITED (AU) | 1987-05-19 | — | — | US | disclosed |
| US-4652303-A | Herbicidal 5-(acylphenyl)cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-03-24 | — | — | US | disclosed |
| EP-0085529-B1 | CYCLOHEXANE DIONE DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND METHODS OF PREPARING THEM | ICI AUSTRALIA LIMITED (AU) | 1986-08-27 | — | — | EP | disclosed |
| EP-0133349-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1985-02-20 | — | — | EP | disclosed |
| EP-0085529-A2 | Cyclohexane dione derivatives, their use as herbicides, herbicidal compositions containing them, and methods of preparing them | ICI AUSTRALIA LIMITED (AU) | 1983-08-10 | — | — | EP | disclosed |
| EP-0080301-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112015-A1 | Substituted dihydropyridines and methods of use | C3AR1, C5AR1, C5AR2 | ABCB1 1958/4885ALDH1A1 1488/4885SMN1; SMN2 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.