Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.80 |
| ▸ | HPGD | P15428 | 5/20 | 0.80 |
| ▸ | MEN1 | O00255 | 4/20 | 0.80 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.55 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18559068 | 0.89 | HPGD (1.00) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL18559069 | 0.89 | HPGD (1.00) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL5335903 | 0.88 | HPGD (0.76) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL5329766 | 0.83 | GAA (0.64) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL5338355 | 0.82 | TSHR (0.59) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL5422195 | 0.82 | GAA (0.62) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL13831971 | 0.82 | TSHR (0.72) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL14542264 | 0.82 | HPGD (0.65) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL18556574 | 0.81 | HPGD (1.00) | KMT2AHPGDMEN1MDM2ALDH1A1 | |
| SCHEMBL18556573 | 0.80 | HPGD (1.00) | KMT2AHPGDMEN1MDM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |