Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.76 |
| ▸ | GAA | P10253 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336800 | 0.88 | KMT2A (0.80) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL18559068 | 0.87 | HPGD (1.00) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL18559069 | 0.87 | HPGD (1.00) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL18556574 | 0.84 | HPGD (1.00) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL18556573 | 0.83 | HPGD (1.00) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL18556575 | 0.82 | HPGD (1.00) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL5327274 | 0.82 | GAA (0.79) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL13831971 | 0.81 | TSHR (0.72) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL14542264 | 0.78 | HPGD (0.65) | HPGDKMT2AMEN1MDM2GAA | |
| SCHEMBL5480773 | 0.78 | ALDH1A1 (0.78) | GAAALDH1A1TSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047394-A2 | THIOTRIAZOLYL DERIVATIVES | EPIX DELAWARE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |