SCHEMBL5337067

SCHEMBL5337067

CC(C)COP(=O)(S)OCC(C)C

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.34
GAA P10253 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
LMNA P02545 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL23014452 0.81 GAA (0.37) ALDH1A1CYP3A4GAANPSR1MEN1
SCHEMBL3924417 0.81
SCHEMBL10580539 0.81 GAA (0.37) ALDH1A1CYP3A4GAANPSR1MEN1
SCHEMBL23014392 0.81 GAA (0.37) ALDH1A1CYP3A4GAANPSR1MEN1
SCHEMBL15545751 0.77 CYP3A4 (0.35) ALDH1A1CYP3A4GAANPSR1MEN1
SCHEMBL133326 0.77 TSHR (0.45) ALDH1A1CYP3A4GAANPSR1MEN1
SCHEMBL11701484 0.74 ANPEP (0.46) CYP3A4NPSR1MEN1KMT2ALMNA
SCHEMBL5407738 0.74 NPSR1 (0.39) ALDH1A1CYP3A4GAANPSR1MEN1
SCHEMBL8971191 0.74
SCHEMBL9259355 0.74 ALDH1A1 (0.38) ALDH1A1CYP3A4GAANPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434464-B1 Transition-metal free Lubricant ETHYL PETROLEUM ADDITIVES LTD (GB) 1995-02-15 EP claimed
US-5254272-A Lubricant compositions with metal-free antiwear or load-carrying additives and amino succinate esters ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-10-19 US claimed
EP-0434464-A1 Transition-metal free Lubricant ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1991-06-26 EP claimed
US-11667866-B2 Phosphorous containing compounds and uses thereof AFTON CHEMICAL CORPORATION (US) 2023-06-06 US disclosed
CN-114369488-B Gear oil additive composition and preparation method thereof 中国石油天然气股份有限公司 2023-02-07 CN disclosed
CN-114369488-A Gear oil additive composition and preparation method thereof 中国石油天然气股份有限公司 2022-04-19 CN disclosed
JP-2007131848-A LUBRICANT COMPOSITION AFTON CHEMICAL CORP 2007-05-31 JP disclosed
EP-0434464-B1 Transition-metal free Lubricant ETHYL PETROLEUM ADDITIVES LTD (GB) 1995-02-15 EP disclosed
US-5254272-A Lubricant compositions with metal-free antiwear or load-carrying additives and amino succinate esters ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1993-10-19 US disclosed
EP-0434464-A1 Transition-metal free Lubricant ETHYL PETROLEUM ADDITIVES LIMITED (GB) 1991-06-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667866-B2 Phosphorous containing compounds and uses thereof SOST, PHOSPHO1, PSPH ALDH1A1 4608/4885CYP3A4 4745/4885GAA 3912/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.