Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 4/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5343854 | 0.90 | PTPN1 (0.47) | PRNPRXFP1PTPN1ALDH1A1HPGD | |
| SCHEMBL5340347 | 0.88 | F9 (0.41) | F9PRNPRXFP1PTPN1CASP3 | |
| SCHEMBL5341879 | 0.88 | F9 (0.41) | F9PRNPRXFP1PTPN1CASP3 | |
| SCHEMBL5337145 | 0.86 | F9 (0.44) | F9PRNPRXFP1PTPN1CASP3 | |
| SCHEMBL5335292 | 0.84 | PTPN1 (0.36) | PRNPRXFP1PTPN1ALDH1A1HPGD | |
| SCHEMBL5344423 | 0.80 | PTPN1 (0.48) | PRNPRXFP1PTPN1ALDH1A1HPGD | |
| SCHEMBL5338631 | 0.79 | PTPN1 (0.46) | PRNPRXFP1PTPN1CASP7ALDH1A1 | |
| SCHEMBL5335829 | 0.79 | PTPN1 (0.34) | PRNPRXFP1PTPN1ALDH1A1HPGD | |
| SCHEMBL5344186 | 0.78 | F9 (0.41) | F9ABCB1CASP3CASP7CASP9 | |
| SCHEMBL5337091 | 0.78 | RXFP1 (0.46) | F9PRNPRXFP1PTPN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163954-B2 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2007-01-16 | — | — | US | disclosed |
| EP-1664015-A1 | SUBSTITUTED NAPHTHYL BENZOTHIOPHENE ACIDS | Wyeth (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005030750-A1 | SUBSTITUTED NAPHTHYL BENZOTHIOPHENE ACIDS | WYETH (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070587-A1 | Substituted naphthyl benzothiophene acids | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070587-A1 | Substituted naphthyl benzothiophene acids | TST, GNPAT, NUDT1 | F9 4698/4885PRNP 2935/4885RXFP1 4872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.