Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | GSR | P00390 | 2/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1673261 | 0.76 | IDO1 (0.40) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL5318743 | 0.70 | MAPT (0.37) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL8694063 | 0.69 | IDO1 (0.41) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL12629098 | 0.68 | HSPA1A (0.54) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL14842656 | 0.67 | GAA (0.40) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL28252886 | 0.66 | GAA (0.39) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL28278551 | 0.64 | MAPT (0.43) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL28253646 | 0.63 | GAA (0.37) | KMT2AMAPTGAAKDM4EMEN1 | |
| SCHEMBL31589753 | 0.63 | ALDH1A1 (0.41) | KMT2AMAPTGAAMEN1IDO1 | |
| SCHEMBL9389041 | 0.61 | PTPN1 (0.36) | KMT2AMAPTGAAMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007079086-A1 | PYRAZOLOALKYL SUBSTITUTED IMIDAZO RING COMPOUNDS AND METHODS | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2007-07-12 | — | — | WO | disclosed |