Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | CALML3 | P27482 | 6/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337945 | 1.00 | MAOA (0.56) | MAOAMAOBCALML3CYP2C19CYP3A4 | |
| Lithium Ion SCHEMBL5337918 | 0.94 | MAOA (0.50) | MAOAMAOBCALML3CYP2C19CYP3A4 | |
| SCHEMBL5344382 | 0.90 | F10 (0.45) | MAOAMAOBCALML3BRD4CREBBP | |
| SCHEMBL5344374 | 0.90 | F10 (0.45) | MAOAMAOBCALML3BRD4CREBBP | |
| SCHEMBL16686214 | 0.85 | MAOA (0.56) | MAOAMAOBCALML3CYP2C19CYP3A4 | |
| SCHEMBL5341828 | 0.85 | MAOB (0.40) | MAOAMAOBCALML3BRD4CREBBP | |
| SCHEMBL5341840 | 0.85 | MAOB (0.40) | MAOAMAOBCALML3BRD4CREBBP | |
| SCHEMBL5352483 | 0.83 | MAOA (0.45) | MAOAMAOBCALML3BRD4CREBBP | |
| SCHEMBL5352491 | 0.83 | MAOA (0.45) | MAOAMAOBCALML3BRD4CREBBP | |
| SCHEMBL14437185 | 0.83 | MAOA (0.41) | MAOAMAOBCALML3CYP3A4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |