Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352483 | 1.00 | MAOA (0.45) | MAOABRD4CREBBPEZH2MAOB | |
| Ammonia Solution, Strong SCHEMBL5342207 | 0.99 | MAOA (0.44) | MAOABRD4CREBBPEZH2MAOB | |
| SCHEMBL14437182 | 0.90 | MAOA (0.42) | MAOABRD4CREBBPEZH2MAOB | |
| SCHEMBL5338264 | 0.89 | BRD4 (0.40) | MAOABRD4CREBBPEZH2MAOB | |
| SCHEMBL5338261 | 0.89 | BRD4 (0.40) | MAOABRD4CREBBPEZH2MAOB | |
| SCHEMBL5351344 | 0.89 | BRD4 (0.40) | MAOABRD4CREBBPEZH2MAOB | |
| SCHEMBL5351336 | 0.89 | BRD4 (0.40) | MAOABRD4CREBBPEZH2MAOB | |
| SCHEMBL5337231 | 0.85 | MAOA (0.47) | MAOABRD4CREBBPMAOBPTGER3 | |
| SCHEMBL5337225 | 0.85 | MAOA (0.47) | MAOABRD4CREBBPMAOBPTGER3 | |
| SCHEMBL5337945 | 0.83 | MAOA (0.56) | MAOABRD4CREBBPEZH2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088478-A1 | INDAZOLE OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | PFIZER PRODUCTS INC. (US) | 2007-08-09 | — | — | WO | disclosed |