Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 2/20 | 0.40 |
| ▸ | AKT2 | P31751 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347257 | 0.83 | CNR1 (0.57) | CNR1SLC2A1MEN1ALDH1A1MAPT | |
| SCHEMBL5338205 | 0.83 | CNR1 (0.57) | CNR1SLC2A1MEN1ALDH1A1MAPT | |
| SCHEMBL4080188 | 0.81 | CNR1 (0.77) | CNR1ALPLOPRL1 | |
| SCHEMBL5343515 | 0.76 | CNR1 (0.48) | CNR1SLC2A1ALDH1A1TOP2AAKT1 | |
| Hydrochloric Acid SCHEMBL5348937 | 0.72 | CNR1 (0.56) | CNR1SLC2A1AKT1AKT2 | |
| SCHEMBL5348158 | 0.71 | AKT1 (0.60) | AKT1AKT2 | |
| SCHEMBL5333928 | 0.71 | CNR1 (0.58) | CNR1SLC2A1MEN1ALDH1A1MAPT | |
| SCHEMBL5343483 | 0.71 | CYP1A2 (0.59) | SLC2A1ALDH1A1MAPTAKT1AKT2 | |
| SCHEMBL5335420 | 0.70 | NR4A2 (0.57) | CNR1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL4085484 | 0.69 | CNR1 (1.00) | CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |