Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | AKT1 | P31749 | 11/20 | 0.46 |
| ▸ | AKT2 | P31751 | 11/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5347257 | 1.00 | CNR1 (0.57) | CNR1AKT1AKT2SLC2A1GABRD | |
| SCHEMBL5320311 | 0.84 | AKT1 (0.54) | AKT1AKT2SLC2A1GABRDGABRB1 | |
| SCHEMBL5337980 | 0.83 | CNR1 (0.53) | CNR1AKT1AKT2SLC2A1MEN1 | |
| SCHEMBL5346688 | 0.80 | SLC2A1 (0.59) | AKT1AKT2SLC2A1ALDH1A1MAPT | |
| SCHEMBL5341345 | 0.80 | SLC2A1 (0.59) | AKT1AKT2SLC2A1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5348937 | 0.80 | CNR1 (0.56) | CNR1AKT1AKT2SLC2A1 | |
| SCHEMBL5348158 | 0.78 | AKT1 (0.60) | AKT1AKT2 | |
| SCHEMBL5340752 | 0.77 | CNR1 (0.53) | CNR1AKT1AKT2SLC2A1TUBB4A | |
| SCHEMBL5489046 | 0.75 | AKT1 (0.46) | AKT1AKT2GABRDGABRB1GABRA4 | |
| SCHEMBL5340340 | 0.73 | SLC2A1 (0.64) | AKT1AKT2SLC2A1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |