Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 11/20 | 0.54 |
| ▸ | AKT2 | P31751 | 11/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | CDH1 | P12830 | 1/20 | 0.44 |
| ▸ | APC | P25054 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348158 | 0.94 | AKT1 (0.60) | AKT1AKT2CDH1APCCTNNB1 | |
| SCHEMBL5489046 | 0.89 | AKT1 (0.46) | AKT1AKT2DHODHCDH1APC | |
| SCHEMBL5347759 | 0.85 | AKT1 (0.52) | AKT1AKT2DHODHSLC2A1 | |
| SCHEMBL5341132 | 0.85 | CDH1 (0.48) | AKT1AKT2DHODHCDH1APC | |
| SCHEMBL5338205 | 0.84 | CNR1 (0.57) | AKT1AKT2GABRDGABRB1GABRA4 | |
| SCHEMBL5347257 | 0.84 | CNR1 (0.57) | AKT1AKT2GABRDGABRB1GABRA4 | |
| SCHEMBL5346688 | 0.83 | SLC2A1 (0.59) | AKT1AKT2SLC2A1 | |
| SCHEMBL5341345 | 0.83 | SLC2A1 (0.59) | AKT1AKT2SLC2A1 | |
| SCHEMBL3498373 | 0.82 | CDH1 (0.50) | AKT1AKT2CDH1APCCTNNB1 | |
| SCHEMBL3498796 | 0.80 | CYP1A2 (0.49) | AKT1AKT2DHODHCDH1APC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |