SCHEMBL5338248

SCHEMBL5338248

Oc1ccc(C(S)c2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.57
TDO2 P48775 1/20 0.57
TDP1 Q9NUW8 2/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA3 P07451 2/20 0.48
CA4 P22748 2/20 0.48
CA9 Q16790 2/20 0.48
CA14 Q9ULX7 2/20 0.48
GLA P06280 1/20 0.48
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
LMNA P02545 3/20 0.44
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 3/20 0.44
ESR1 P03372 5/20 0.44
ESR2 Q92731 5/20 0.44
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132873 0.84 DPP4 (0.47) LMNAMTORRAB9A
Hydrochloric Acid SCHEMBL157812 0.81 DPP4 (0.45) IDO1TDO2TDP1ALDH1A1CYP3A4
Iodide SCHEMBL1043794 0.81 DPP4 (0.45) LMNAMTORRAB9A
SCHEMBL503028 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL22694327 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL36791 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL19314626 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL17995329 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL982047 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1
SCHEMBL14163315 0.79 IDO1 (0.56) IDO1TDO2TDP1CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115135407-A Two-layer seamless capsule with water-soluble composition as inner coating 富士胶囊股份有限公司 2022-09-30 CN disclosed
CN-112430404-B Check valve casting and machining process thereof 温州市海格阀门有限公司 2022-04-08 CN disclosed
CN-112430404-A Check valve casting and machining process thereof 温州市海格阀门有限公司 2021-03-02 CN disclosed
CN-106536654-B Adhesive, adhesive body, and method for producing adhesive body 株式会社可乐丽 2021-01-08 CN disclosed
CN-105579436-B Onium salts and compositions comprising the same 旭化成株式会社 2020-12-22 CN disclosed
CN-107709496-B Adhesive, adhesive body, and method for producing adhesive body 株式会社可乐丽 2020-04-24 CN disclosed
US-10189781-B2 Onium salt and composition comprising the same ASAHI KASEI E-MATERIALS CORPORATION (JP) 2019-01-29 US disclosed
US-20160229801-A1 ONIUM SALT AND COMPOSITION COMPRISING THE SAME ASAHI KASEI E-MATERIALS CORPORATION (JP) 2016-08-11 US disclosed
US-7297461-B2 Radiation sensitive resin composition JSR CORPORATION (JP) 2007-11-20 US disclosed
EP-1726608-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2006-11-29 EP disclosed
US-20050171226-A1 Radiation sensitive resin composition JSR CORPORATION (JP) 2005-08-04 US disclosed
US-20030170561-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2003-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10189781-B2 Onium salt and composition comprising the same EIF2B5, HSF1, INPP5A IDO1 2540/4885TDO2 3807/4885TDP1 4427/4885
US-20160229801-A1 ONIUM SALT AND COMPOSITION COMPRISING THE SAME EIF2B5, HSF1, INPP5A IDO1 2540/4885TDO2 3807/4885TDP1 4427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.