Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH2 | Q9NR71 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.53 |
| ▸ | CETP | P11597 | 3/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7586220 | 0.93 | FAAH (0.53) | ASAH2FAAHDEGS1CETPTHRB | |
| Hydrochloric Acid SCHEMBL28383541 | 0.92 | FAAH (0.57) | ASAH2FAAHMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL28980110 | 0.91 | ASAH2 (0.52) | ASAH2FAAHDEGS1CETPTHRB | |
| SCHEMBL3166339 | 0.90 | FAAH (0.59) | ASAH2FAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL2975259 | 0.90 | FAAH (0.59) | ASAH2FAAHMEN1KMT2AALDH1A1 | |
| SCHEMBL28927369 | 0.90 | ASAH2 (0.53) | ASAH2FAAHDEGS1CETPTHRB | |
| Hydrochloric Acid SCHEMBL25267066 | 0.88 | FAAH (0.53) | ASAH2FAAHDEGS1CETPTHRB | |
| Hydrochloric Acid SCHEMBL4624704 | 0.88 | FAAH (0.53) | ASAH2FAAHDEGS1CETPTHRB | |
| SCHEMBL25266302 | 0.86 | FAAH (0.55) | ASAH2FAAHDEGS1CETPTHRB | |
| Hydrochloric Acid SCHEMBL5349551 | 0.86 | LPAR3 (0.48) | ASAH2FAAHDEGS1CETPTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108853607-A | A kind of insulin needle surface siliconization inorganic agent | 广州市爱创医疗科技有限公司 | 2018-11-23 | — | — | CN | disclosed |
| US-7189687-B2 | Softener composition | KAO CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| US-20050090423-A1 | Softener composition | KAO CORPORATION | 2005-04-28 | — | — | US | disclosed |
| EP-1264874-B1 | Softener composition | KAO CORP (JP) | 2005-03-02 | — | — | EP | disclosed |
| US-6838427-B2 | For fabrics, imparts high softening regardless of the state of the rinsing water; specified mole ratio of 2 types of optionally ester or amide-functional tertiary amines or their ammonium salts and a sulfonate or sulfate anionic surfactant | KAO CORPORATION (JP) | 2005-01-04 | — | — | US | disclosed |
| US-20030060389-A1 | Softener composition | KAO CORPORATION (JP) | 2003-03-27 | — | — | US | disclosed |
| EP-1264874-A1 | Softener composition | Kao Corporation (JP) | 2002-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090423-A1 | Softener composition | C1R, H1-10, C1S | ASAH2 1788/4885FAAH 61/4885DEGS1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.