Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3692617 | 0.87 | — | — | |
| SCHEMBL10976154 | 0.76 | KEAP1 (0.41) | KEAP1NFE2L2ALDH1A1TSHRTP53 | |
| SCHEMBL7871768 | 0.76 | EPHX1 (0.37) | KEAP1NFE2L2ALDH1A1TSHRTP53 | |
| SCHEMBL29037985 | 0.75 | KEAP1 (0.40) | KEAP1NFE2L2ALDH1A1TSHRTP53 | |
| SCHEMBL2846765 | 0.74 | KEAP1 (0.42) | KEAP1NFE2L2ALDH1A1TSHRCES2 | |
| SCHEMBL873007 | 0.74 | KEAP1 (0.42) | KEAP1NFE2L2ALDH1A1TSHRCES2 | |
| SCHEMBL8328164 | 0.74 | KEAP1 (0.42) | KEAP1NFE2L2ALDH1A1TSHRCES2 | |
| SCHEMBL22341281 | 0.73 | KEAP1 (0.38) | KEAP1NFE2L2ALDH1A1TSHRTP53 | |
| SCHEMBL21269265 | 0.72 | KEAP1 (0.41) | KEAP1NFE2L2ALDH1A1TSHRCES2 | |
| SCHEMBL66869 | 0.72 | KEAP1 (0.45) | KEAP1NFE2L2ALDH1A1TSHRCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114894952-B | Thin-layer identification method of Shang Quanfang six Chinese herbal medicines in angelica sinensis | 国药集团广东环球制药有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-114894952-A | Thin-layer identification method for six traditional Chinese medicine ingredients of angelica Jianzhong decoction | 国药集团广东环球制药有限公司 | 2022-08-12 | — | — | CN | claimed |
| EP-0550875-B2 | PROCESS FOR THE PRODUCTION OF AN IMPLANTABLE POLYMERIC DEVICE CONTAINING PHARMACEUTICAL AGENTS | SCHIERHOLZ JOERG DR DR (DE) | 2007-05-02 | — | — | EP | claimed |
| EP-0550875-B1 | Implantable polymeric device containing pharmaceutical agents and process for its production | SCHIERHOLZ JOERG DR DR (DE) | 1998-04-29 | — | — | EP | claimed |
| CN-114894952-B | Thin-layer identification method of Shang Quanfang six Chinese herbal medicines in angelica sinensis | 国药集团广东环球制药有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-114894952-A | Thin-layer identification method for six traditional Chinese medicine ingredients of angelica Jianzhong decoction | 国药集团广东环球制药有限公司 | 2022-08-12 | — | — | CN | disclosed |