Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14467035 | 0.82 | MAPK14 (0.47) | MAPK14CYP2C9CYP2C19HTR2BMEN1 | |
| SCHEMBL5323872 | 0.82 | MAPK14 (0.54) | MAPK14CYP2C9CYP2C19HTR2BMEN1 | |
| SCHEMBL5336016 | 0.78 | MAPK14 (0.46) | MAPK14CYP2C9CYP2C19HTR2BMEN1 | |
| SCHEMBL14467011 | 0.76 | MAPK14 (0.48) | MAPK14CYP2C9CYP2C19HTR2BMEN1 | |
| SCHEMBL5319166 | 0.72 | MAPK14 (0.57) | MAPK14CYP2C9CYP2C19HTR2B | |
| SCHEMBL5323974 | 0.72 | MAPK14 (0.57) | MAPK14CYP2C9CYP2C19HTR2BCCR3 | |
| Hydrochloric Acid SCHEMBL5321355 | 0.72 | MAPK14 (0.56) | MAPK14CYP2C9CYP2C19HTR2BCCR3 | |
| SCHEMBL5323972 | 0.71 | MAPK14 (0.55) | MAPK14CYP2C9CYP2C19HTR2BCHRM2 | |
| SCHEMBL13936069 | 0.71 | MAPK14 (0.62) | MAPK14CYP2C9CYP2C19HTR2BMEN1 | |
| SCHEMBL14473858 | 0.70 | MAPK14 (0.54) | MAPK14CYP2C9CYP2C19HTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082079-A2 | PIPERIDINE AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | WO | disclosed |