Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534794 | 0.84 | PTGDR2 (0.51) | PTGDR2CCNE2CCNE1CDK2 | |
| SCHEMBL534080 | 0.83 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL534920 | 0.81 | PTGDR2 (0.49) | PTGDR2SMN1; SMN2 | |
| SCHEMBL2572569 | 0.80 | PTGDR2 (0.56) | PTGDR2CCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL19614973 | 0.77 | PTGDR2 (0.44) | PTGDR2DHFRCCNB2CDK1CCNB1 | |
| SCHEMBL2574709 | 0.76 | PTGDR2 (0.58) | PTGDR2MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL534118 | 0.76 | PTGDR2 (0.55) | PTGDR2DHFRP2RX3 | |
| SCHEMBL2573403 | 0.75 | PTGDR2 (0.67) | PTGDR2MAPTLMNASMN1; SMN2HTT | |
| SCHEMBL3782624 | 0.75 | PTGDR2 (0.63) | PTGDR2DHFRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2572551 | 0.74 | PTGDR2 (0.62) | PTGDR2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129661-B1 | QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-02-08 | — | — | EP | claimed |