SCHEMBL5340432

SCHEMBL5340432

CCCCC(C)N(c1ccccc1)c1ccc(N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.48
MAPT P10636 4/20 0.48
CYP3A4 P08684 3/20 0.48
TDP1 Q9NUW8 3/20 0.48
KDM4E B2RXH2 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAPK1 P28482 2/20 0.39
PSMD14 O00487 1/20 0.39
TSHR P16473 1/20 0.39
RECQL P46063 1/20 0.39
GFER P55789 1/20 0.39
POLB P06746 1/20 0.37
CSNK1E P49674 1/20 0.35
HTT P42858 2/20 0.35
ALOX12 P18054 1/20 0.35
TP53 P04637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28737807 0.95 ALDH1A1 (0.47) ALDH1A1MAPTCYP3A4TDP1KDM4E
SCHEMBL3457890 0.94 ALDH1A1 (0.46) ALDH1A1MAPTCYP3A4TDP1KDM4E
SCHEMBL4621269 0.90 ALDH1A1 (0.52) ALDH1A1MAPTCYP3A4TDP1KDM4E
SCHEMBL11232615 0.87 CYP17A1 (0.40) ALDH1A1MAPTKDM4EPOLBHTT
SCHEMBL16874342 0.86 TSHR (0.38) ALDH1A1MAPTCYP3A4TDP1KDM4E
SCHEMBL30691822 0.84 SIGMAR1 (0.42) ALDH1A1POLBCSNK1ESIGMAR1NPC1
SCHEMBL3957690 0.83 ALDH1A1 (0.47) ALDH1A1MAPTCYP3A4TDP1KDM4E
SCHEMBL2493913 0.83 CSNK1E (0.41) ALDH1A1POLBCSNK1ESIGMAR1NPC1
SCHEMBL571119 0.83 CSNK1E (0.41) ALDH1A1POLBCSNK1ESIGMAR1NPC1
SCHEMBL28068560 0.83 CSNK1E (0.41) ALDH1A1POLBCSNK1ESIGMAR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101825616-B Method for analyzing engine oil degradation GM GLOBAL TECH OPERATIONS INC 2014-05-07 CN disclosed
CN-101825616-A Method for analyzing engine oil degradation GM GLOBAL TECH OPERATIONS INC 2010-09-08 CN disclosed
US-7195828-B2 Lubricant for magnetic recording medium and use thereof SHELL OIL COMPANY (US) 2007-03-27 US disclosed
US-20020114980-A1 Lubricant for magnetic recording medium and use thereof PENNZOIL-QUAKER STATE COMPANY 2002-08-22 US disclosed