Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335110 | 0.88 | AGPAT2 (0.43) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5340379 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL19663011 | 0.79 | NPC1 (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5337103 | 0.78 | AGPAT2 (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5334323 | 0.73 | SYK (0.45) | KDM4EALDH1A1MAPTRECQL | |
| SCHEMBL5340643 | 0.73 | F2RL3 (0.38) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL31154071 | 0.73 | NPC1 (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL2964184 | 0.73 | KDM4E (0.52) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL2954863 | 0.73 | TOP2A (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL2401083 | 0.72 | NPC1 (0.54) | KDM4EALDH1A1TSHRMAPTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |