Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGPAT2 | O15120 | 2/20 | 0.44 |
| ▸ | F2RL3 | Q96RI0 | 8/20 | 0.43 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5335110 | 0.86 | AGPAT2 (0.43) | AGPAT2F2RL3CEPT1MEN1KMT2A | |
| SCHEMBL5341017 | 0.85 | F2RL3 (0.39) | AGPAT2F2RL3PSEN1PSEN2APH1B | |
| SCHEMBL14436018 | 0.80 | F2RL3 (0.43) | AGPAT2F2RL3CEPT1MEN1KMT2A | |
| SCHEMBL5340563 | 0.78 | KDM4E (0.48) | AGPAT2F2RL3PSEN1PSEN2APH1B | |
| SCHEMBL5339446 | 0.77 | L3MBTL1 (0.49) | F2RL3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5332553 | 0.75 | CEPT1 (0.51) | AGPAT2F2RL3CEPT1MEN1KMT2A | |
| SCHEMBL6099363 | 0.72 | KDM4E (0.34) | F2RL3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5340643 | 0.72 | F2RL3 (0.38) | F2RL3MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15522258 | 0.70 | AGPAT2 (0.39) | AGPAT2F2RL3CEPT1TP53SMN1; SMN2 | |
| SCHEMBL31154071 | 0.69 | NPC1 (0.50) | AGPAT2F2RL3CEPT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262301-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2007-08-28 | — | — | US | disclosed |
| US-7105680-B1 | Zinc-chelating ratiometric fluorescent probes and related methods | NORTHWESTERN UNIVERSITY (US) | 2006-09-12 | — | — | US | disclosed |