Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534060 | 0.89 | AR (0.36) | ARMBOAT4 | |
| SCHEMBL533987 | 0.88 | AR (0.36) | ARMBOAT4 | |
| SCHEMBL533998 | 0.83 | PTGDR2 (0.40) | AR | |
| SCHEMBL534128 | 0.82 | MAPT (0.35) | AR | |
| SCHEMBL2582687 | 0.82 | ROCK2 (0.35) | — | |
| SCHEMBL534857 | 0.81 | PTGDR2 (0.39) | AR | |
| SCHEMBL2574953 | 0.80 | PTGDR2 (0.44) | DCTPP1 | |
| SCHEMBL2579240 | 0.80 | PTGDR2 (0.34) | — | |
| SCHEMBL2570608 | 0.80 | KCNH2 (0.36) | MBOAT4 | |
| SCHEMBL2581492 | 0.80 | KCNH2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129661-B1 | QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-02-08 | — | — | EP | claimed |