Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534080 | 0.89 | PTGDR2 (0.51) | PTGDR2TNKSPARP1TNKS2CNR2 | |
| SCHEMBL534795 | 0.88 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL534041 | 0.78 | PTGDR2 (0.46) | PTGDR2PARP1 | |
| SCHEMBL3664112 | 0.77 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL534794 | 0.76 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL534920 | 0.73 | PTGDR2 (0.49) | PTGDR2PARP1 | |
| SCHEMBL534002 | 0.73 | PTGDR2 (0.59) | PTGDR2 | |
| SCHEMBL3776129 | 0.73 | PTGDR2 (0.78) | PTGDR2 | |
| SCHEMBL3770942 | 0.72 | PTGDR2 (0.74) | PTGDR2 | |
| SCHEMBL3772517 | 0.72 | PTGDR2 (0.66) | PTGDR2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129661-B1 | QUINOLINE DERIVATIVES AS CRTH2 RECEPTOR LIGANDS | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2012-02-08 | — | — | EP | claimed |