Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRG | P62508 | 2/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 3/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14590406 | 0.79 | HTT (0.41) | BRD4 | |
| SCHEMBL434849 | 0.76 | ESRRG (0.55) | ESRRGSIGMAR1MGAMLMNA | |
| SCHEMBL5346670 | 0.75 | ALDH1A1 (0.34) | LMNA | |
| SCHEMBL24215776 | 0.71 | HTR7 (0.53) | SIGMAR1DRD3 | |
| SCHEMBL5341329 | 0.70 | HSP90AA1 (0.39) | ESRRGSOS1 | |
| SCHEMBL28961627 | 0.68 | MEN1 (0.33) | DRD3LMNA | |
| SCHEMBL9989007 | 0.67 | ALDH1A1 (0.36) | DRD3LMNA | |
| SCHEMBL6922776 | 0.65 | ALDH1A1 (0.38) | ESRRGLMNA | |
| SCHEMBL31468540 | 0.62 | CXCR4 (0.43) | CXCR4 | |
| SCHEMBL194639 | 0.62 | KDM1A (0.50) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7164018-B2 | Polymers based on N-carbamyl-N'-dimethylsilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-16 | — | — | US | disclosed |
| US-7164018-B2 | Polymers based on N-carbamyl-N'-dimethylsilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-01-16 | — | — | US | disclosed |
| US-20040186243-A1 | Polymers based on N-carbamyl-N'-dimethylsilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-09-23 | — | — | US | disclosed |
| US-6740712-B2 | SILICON LINKERS BASED ON CARBAMYL PIPERAZINE MOIETY; USE IN SOLID PHASE SYNTHESIS OF COMPOUNDS OR LIBRARIES OF COMPOUNDS EMBRACING A PHENYL RING IN THEIR STRUCTURE | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2004-05-25 | — | — | US | disclosed |
| US-20020120072-A1 | Polymers based on N-carbamyl-N'-dimethysilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120072-A1 | Polymers based on N-carbamyl-N'-dimethysilyl methyl-piperazine traceless linkers for the solid phase synthesis of phenyl based libraries | DOT1L, DNMT3L, SMYD2 | ESRRG 4148/4885SOS1 1557/4885CXCR4 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.