Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6343013 | 0.89 | TSHR (0.39) | TSHRLMNAPOLBALDH1A1RAB9A | |
| SCHEMBL6620832 | 0.89 | TSHR (0.39) | TSHRLMNAPOLBALDH1A1RAB9A | |
| SCHEMBL2408506 | 0.86 | MGAM (0.45) | TSHRLMNAPOLBALDH1A1RAB9A | |
| SCHEMBL2721040 | 0.86 | — | — | |
| SCHEMBL12686975 | 0.82 | SMN1; SMN2 (0.47) | TSHRLMNAPOLBALDH1A1RAB9A | |
| SCHEMBL1881523 | 0.82 | ALDH1A1 (0.46) | POLBALDH1A1L3MBTL1MGAMGAA | |
| SCHEMBL1439129 | 0.82 | TDP1 (0.48) | POLBALDH1A1L3MBTL1MGAMGAA | |
| SCHEMBL7282596 | 0.81 | TSHR (0.50) | TSHRLMNAPOLBALDH1A1RAB9A | |
| SCHEMBL12986428 | 0.81 | L3MBTL1 (0.33) | POLBALDH1A1RAB9AL3MBTL1GAA | |
| SCHEMBL17872673 | 0.81 | TSHR (0.47) | TSHRLMNAPOLBALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1552344-A4 | A METHOD FOR THE REMOVAL OF AN IMAGING LAYER FROM A SEMICONDUCTOR SUBSTRATE STACK | FUJIFILM ELECTRONIC MATERIALS (US) | 2009-04-01 | — | — | EP | claimed |
| US-7011935-B2 | Method for the removal of an imaging layer from a semiconductor substrate stack | ARCH SPECIALTY CHEMICALS, INC. (US) | 2006-03-14 | — | — | US | claimed |
| EP-1552344-A2 | A METHOD FOR THE REMOVAL OF AN IMAGING LAYER FROM A SEMICONDUCTOR SUBSTRATE STACK | Arch Specialty Chemicals, Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| US-20040116312-A1 | Method for the removal of an imaging layer from a semiconductor substrate stack | ARCH SPECIALTY CHEMICALS, INC. | 2004-06-17 | — | — | US | claimed |
| WO-2004027518-A2 | A METHOD FOR THE REMOVAL OF AN IMAGING LAYER FROM A SEMICONDUCTOR SUBSTRATE STACK | ARCH SPECIALTY CHEMICALS, INC. (US) | 2004-04-01 | — | — | WO | claimed |
| US-12545689-B2 | Macrocyclic LRRK2 kinase inhibitors | ONCODESIGN PRECISION MEDICINE (FR) | 2026-02-10 | — | — | US | disclosed |
| CN-118359588-A | Compounds as CTPS1 inhibitors | 杭州英创医药科技有限公司 | 2024-07-19 | — | — | CN | disclosed |
| US-20230357269-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | ONCODESIGN PRECISION MEDICINE (FR) | 2023-11-09 | — | — | US | disclosed |
| US-20230357269-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | ONCODESIGN PRECISION MEDICINE (FR) | 2023-11-09 | — | — | US | disclosed |
| US-20230357269-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | ONCODESIGN PRECISION MEDICINE (FR) | 2023-11-09 | — | — | US | disclosed |
| CN-111868063-B | PI4KIII beta inhibitors | 葛兰素史克知识产权开发有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-111527090-B | Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors | 拜耳公司 | 2023-05-26 | — | — | CN | disclosed |
| EP-0677524-A1 | Thieno[3,2-F][1,2,4]triazolo[4,3-A][1,4]diazepine derivatives as PAF antagonists | Eisai Co., Ltd. (JP) | 1995-10-18 | — | — | EP | disclosed |
| US-5438045-A | An 3-acetyl-6-phenyl-2,3,4,5-tetrahydro-8h-pyrido(4'3':4,5)-thieno(3,2 -f)(1,2,4)triazolo(4,3-a)(1,4)diazepine derivative; antiallergens; asthma; antiplatelet activating factor activity | EISAI CO., LTD. (JP) | 1995-08-01 | — | — | US | disclosed |
| US-5409909-A | Antiallergens | EISAI CO., LTD. (JP) | 1995-04-25 | — | — | US | disclosed |
| US-5382579-A | Platelet activating factor antagonists; antiallergens; asthma | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0606103-A1 | Thieno 3.2-f 1,2,4 triazolo 4,3-a 1,4 -diazepine derivatives as PAF antagonists | Eisai Co., Ltd. (JP) | 1994-07-13 | — | — | EP | disclosed |
| US-5304553-A | Antiallergens; platelet activating factor inhibitor | EISAI CO., LTD. (JP) | 1994-04-19 | — | — | US | disclosed |
| US-5221671-A | Antiallergens, bronchodilator agents | EISAI CO., LTD. (JP) | 1993-06-22 | — | — | US | disclosed |
| EP-0367110-A1 | 1,4-diazepine derivative and its pharmaceutical use | Eisai Co., Ltd. (JP) | 1990-05-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545689-B2 | Macrocyclic LRRK2 kinase inhibitors | LRRK2, SNCA, ROS1 | TSHR 1198/4885LMNA 895/4885POLB 1471/4885 |
| US-20230357269-A1 | NEW MACROCYCLIC LRRK2 KINASE INHIBITORS | LRRK2, RIN1, GRK3 | TSHR 1552/4885LMNA 1734/4885POLB 2713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.