Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5340915 | 1.00 | CHRM2 (0.35) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL1286642 | 0.73 | MAPK1 (0.40) | CHRM2CHRM4LMNAMEN1KMT2A | |
| SCHEMBL21153824 | 0.73 | MAPK1 (0.40) | CHRM2CHRM4LMNAMEN1KMT2A | |
| SCHEMBL2116916 | 0.73 | MAPK1 (0.40) | CHRM2CHRM4LMNAMEN1KMT2A | |
| SCHEMBL6081100 | 0.68 | CRHBP (0.38) | LMNASLC6A4KMT2A | |
| SCHEMBL6081516 | 0.68 | HTR2A (0.36) | KMT2A | |
| SCHEMBL13907595 | 0.67 | MEN1 (0.43) | LMNAMEN1KMT2A | |
| SCHEMBL2477286 | 0.67 | MAOB (0.38) | MEN1KMT2A | |
| SCHEMBL2478791 | 0.67 | SLC6A2 (0.40) | SLC6A2SLC6A4 | |
| SCHEMBL2482801 | 0.67 | MAOB (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007098356-A1 | CONGENERS OF MILNACIPRAN AS MONOAMINE RE-UPTAKE | NEUROCRINE BIOSCIENCES, INC. (US) | 2007-08-30 | — | — | WO | disclosed |