Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR3 | P32745 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5257922 | 0.82 | SSTR3 (0.47) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL6840775 | 0.82 | SSTR3 (0.47) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5254842 | 0.82 | SSTR3 (0.47) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5258116 | 0.81 | SSTR3 (0.49) | SSTR3CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL5255112 | 0.81 | SSTR3 (0.52) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5340990 | 0.80 | SSTR3 (0.46) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14565670 | 0.76 | SSTR3 (0.51) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5255157 | 0.76 | SSTR3 (0.58) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL5256700 | 0.76 | SSTR3 (0.58) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL14565583 | 0.76 | SSTR3 (0.58) | SSTR3ALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1453801-B1 | SUBSTITUTED 2-AMINO-CYCLOALKANECARBOXAMIDES AND THEIR USE AS CYSTEINE PROTEASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-03-21 | — | — | EP | claimed |