Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | USP21 | Q9UK80 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894982 | 0.83 | PDF (0.62) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL10440716 | 0.83 | PDF (0.62) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL20471420 | 0.82 | C3AR1 (0.53) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL591280 | 0.81 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL2936175 | 0.81 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AMITF | |
| Hydrochloric Acid SCHEMBL29727707 | 0.81 | C3AR1 (0.53) | NPC1RAB9AMEN1KMT2AMITF | |
| Hydrochloric Acid SCHEMBL29365278 | 0.81 | C3AR1 (0.53) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL701212 | 0.81 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2AMITF | |
| SCHEMBL1351202 | 0.81 | CTSL (0.56) | NPC1RAB9AMEN1KMT2AMITF | |
| Hydrochloric Acid SCHEMBL593062 | 0.80 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070162999-A1 | Crop Plant Cystatin Proteinase Inhibitors and Methods of Use | PIONEER HI-BRED INTERNATIONAL, INC. | 2007-07-12 | — | — | US | disclosed |
| US-7205453-B2 | Crop plant cystatin proteinase inhibitors encoding nucleic acids and methods of use | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-20050102717-A1 | Crop plant cystatin proteinase inhibitors and methods of use | PIONEER HI-BRED INTERNATIONAL, INC. | 2005-05-12 | — | — | US | disclosed |
| WO-2005030967-A2 | CROP PLANT CYSTATIN PROTEINASE INHIBITORS AND METHODS OF USE | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20040010118-A1 | Novel proteins and nucleic acids encoding same | CURAGEN CORPORATION | 2004-01-15 | — | — | US | disclosed |
| WO-2002014368-A2 | PROTEINS AND NUCLEIC ACIDS ENCODING THE SAME | CURAGEN CORPORATION (US) | 2002-02-21 | — | — | WO | disclosed |