Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 5/20 | 0.69 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.69 |
| ▸ | OSBP | P22059 | 6/20 | 0.58 |
| ▸ | RORC | P51449 | 4/20 | 0.58 |
| ▸ | OSBP2 | Q969R2 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.58 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.58 |
| ▸ | CRYAB | P02511 | 1/20 | 0.55 |
| ▸ | HMGCR | P04035 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.55 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.54 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27505688 | 0.92 | OSBP (0.69) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL27505687 | 0.92 | OSBP (0.69) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL6387282 | 0.91 | OSBP (0.70) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL6389683 | 0.91 | OSBP (0.70) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL6389117 | 0.91 | OSBP (0.70) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL6391751 | 0.91 | OSBP (0.70) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL6387538 | 0.89 | NPC1L1 (0.70) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL6393065 | 0.89 | NPC1L1 (0.70) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL16015401 | 0.88 | RORC (0.62) | GRIN1GRIN2AOSBPRORCOSBP2 | |
| SCHEMBL6393758 | 0.85 | RORC (0.61) | GRIN1GRIN2AOSBPRORCOSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39678-E1 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2007-06-05 | — | — | US | disclosed |
| US-20050101573-A1 | Meiosis regulating compounds | NOVO NORDISK A/S (DK) | 2005-05-12 | — | — | US | disclosed |
| US-6884796-B2 | Meiosis regulating compounds | NOVONORDISK A/S (DK) | 2005-04-26 | — | — | US | disclosed |
| US-20020183283-A1 | Meiosis regulating compounds | FAARUP PETER (DK) | 2002-12-05 | — | — | US | disclosed |
| US-6407086-B2 | NOVEL STEROL DERIVATIVES USED FOR REGULATING THE MEIOSIS IN OOCYTES AND IN MALE GERM CELLS | NOVO NORDISK A/S (DK) | 2002-06-18 | — | — | US | disclosed |
| US-20010003782-A1 | Meiosis regulating compounds | NOVA NORDISK A/S (DK) | 2001-06-14 | — | — | US | disclosed |
| EP-1077992-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058549-A1 | MEIOSIS REGULATING COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020183283-A1 | Meiosis regulating compounds | SREBF2, SREBF1, TRIP13 | GRIN1 4044/4885GRIN2A 4028/4885OSBP 6/4885 |
| US-20010003782-A1 | Meiosis regulating compounds | SREBF2, SREBF1, TRIP13 | GRIN1 4044/4885GRIN2A 4028/4885OSBP 6/4885 |
| US-20050101573-A1 | Meiosis regulating compounds | SREBF2, SREBF1, TRIP13 | GRIN1 4044/4885GRIN2A 4028/4885OSBP 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.