SCHEMBL534146

SCHEMBL534146

C=C/C=C(/C=C)C(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13619335 1.00
SCHEMBL368601 1.00
SCHEMBL26414869 0.79 ALDH1A1 (0.41)
SCHEMBL17269606 0.77 ALDH1A1 (0.39)
SCHEMBL15963388 0.77 ALDH1A1 (0.39)
SCHEMBL24932910 0.77 ALDH1A1 (0.33)
SCHEMBL13618856 0.77 ALDH1A1 (0.33)
SCHEMBL21533194 0.77 ALDH1A1 (0.39)
SCHEMBL21237920 0.77 ALDH1A1 (0.35)
SCHEMBL19017541 0.77 LMNA (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6075105-A HEATING A MIXTURE OF A FREE RADICAL INITIATOR COMPOUND, A STABLE FREE RADICAL COMPOUND, A FREE RADICAL POLYMERIZABLE MONOMER AND A CROSSLINKING AGENT, COOLING THE MIXTURE TO FORM CROSSLINKED POLYMER WITH NARROW PARTICLE SIZE DISTRIBUTION XEROX CORPORATION (US) 2000-06-13 US claimed
EP-0826697-A2 Polymerization processes and resin particles formed thereby XEROX CORPORATION (US) 1998-03-04 EP claimed
US-9956168-B2 Extended release drug-delivery contact lenses and methods of making MERCY MEDICAL RESEARCH INSTITUTE (US) 2018-05-01 US disclosed
EP-3011383-A2 EXTENDED RELEASE DRUG-DELIVERY CONTACT LENSES AND METHODS OF MAKING Mercy Medical Research Institute (US) 2016-04-27 EP disclosed
US-20140377327-A1 EXTENDED RELEASE DRUG-DELIVERY CONTACT LENSES AND METHODS OF MAKING MERCY MEDICAL RES INST (US) 2014-12-25 US disclosed
WO-2014205252-A2 EXTENDED RELEASE DRUG-DELIVERY CONTACT LENSES AND METHODS OF MAKING MERCY MEDICAL RESEARCH INSTITUTE (US) 2014-12-24 WO disclosed
US-8361492-B2 Drug delivery system and methods of use Ocugenics, LLC (US) 2013-01-29 US disclosed
EP-2413917-A2 DRUG DELIVERY SYSTEM AND METHODS OF USE Ocugenics, Llc (US) 2012-02-08 EP disclosed
US-8083347-B2 Drug delivery system and methods of use Ocugenics, LLC (US) 2011-12-27 US disclosed
WO-2010120489-A2 DRUG DELIVERY SYSTEM AND METHODS OF USE Ocugenics, LLC (US) 2010-10-21 WO disclosed
US-20090269392-A1 Drug Delivery System And Methods Of Use Ocugenics, LLC 2009-10-29 US disclosed
US-20090269391-A1 Drug Delivery System And Methods Of Use OCUGENICS, L.L.C. (US) 2009-10-29 US disclosed
US-6075105-A HEATING A MIXTURE OF A FREE RADICAL INITIATOR COMPOUND, A STABLE FREE RADICAL COMPOUND, A FREE RADICAL POLYMERIZABLE MONOMER AND A CROSSLINKING AGENT, COOLING THE MIXTURE TO FORM CROSSLINKED POLYMER WITH NARROW PARTICLE SIZE DISTRIBUTION XEROX CORPORATION (US) 2000-06-13 US disclosed
EP-0826697-A2 Polymerization processes and resin particles formed thereby XEROX CORPORATION (US) 1998-03-04 EP disclosed
EP-0332011-B1 PREPARATION OF AQUEOUS POLYALKYLMETACRYLATE DISPERSIONS BY POLYMERIZATION IN TWO STAGES, AND THEIR USE IN WOOD COATINGS BASF Aktiengesellschaft (DE) 1991-11-06 EP disclosed
EP-0332011-A1 Preparation of aqueous polyalkylmetacrylate dispersions by polymerization in two stages, and their use in wood coatings BASF Aktiengesellschaft (DE) 1989-09-13 EP disclosed