Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467075 | 1.00 | DRD2 (0.41) | DRD2DRD4DRD3GRIN2BF10 | |
| SCHEMBL467076 | 1.00 | DRD2 (0.41) | DRD2DRD4DRD3GRIN2BF10 | |
| SCHEMBL467236 | 1.00 | DRD2 (0.41) | DRD2DRD4DRD3GRIN2BF10 | |
| SCHEMBL7322347 | 0.89 | BCHE (0.50) | BCHEACHEBACE1CACNA1GOPRL1 | |
| SCHEMBL467141 | 0.89 | BCHE (0.50) | BCHEACHEBACE1CACNA1GOPRL1 | |
| SCHEMBL467140 | 0.89 | BCHE (0.50) | BCHEACHEBACE1CACNA1GOPRL1 | |
| SCHEMBL467142 | 0.89 | BCHE (0.50) | BCHEACHEBACE1CACNA1GOPRL1 | |
| SCHEMBL7331697 | 0.81 | DRD2 (0.46) | DRD2DRD4DRD3GRIN2B | |
| SCHEMBL7323800 | 0.79 | ACHE (0.51) | DRD2DRD4DRD3GRIN2BBCHE | |
| SCHEMBL7323804 | 0.79 | ACHE (0.51) | DRD2DRD4DRD3GRIN2BBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415471-A1 | Use of sigma ligands in opioid-induced hyperalgesia | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2012-02-08 | — | — | EP | disclosed |