SCHEMBL5343162

SCHEMBL5343162

CCC1(C)CC(OC(=O)CCCCC(=O)O)C(C)C(C)(CC)N1OC(C)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.32
FFAR1 O14842 1/20 0.32
CTSK P43235 3/20 0.31
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
CTSB P07858 1/20 0.31
CTSS P25774 1/20 0.31
EPHX2 P34913 1/20 0.31
FAAH O00519 3/20 0.31
CYP2D6 P10635 1/20 0.31
FFAR4 Q5NUL3 1/20 0.30
KMT2A Q03164 1/20 0.30
PTGER4 P35408 1/20 0.30
PTGER2 P43116 1/20 0.30
LMNA P02545 2/20 0.30
CYP2C19 P33261 1/20 0.30
SLC18A3 Q16572 1/20 0.30
NR1I2 O75469 1/20 0.30
ABCB11 O95342 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14590796 0.98 BCHE (0.32) BCHEFFAR1CTSKCTSVCTSL
SCHEMBL5345608 0.94 BCHE (0.36) BCHECTSKCTSVCTSLCTSB
SCHEMBL5342197 0.94 FFAR1 (0.33) FFAR1CTSKCTSVCTSLCTSB
SCHEMBL5337510 0.94 BCHE (0.36) BCHECTSKCTSVCTSLCTSB
SCHEMBL14590788 0.94 BCHE (0.36) BCHECTSKCTSVCTSLCTSB
SCHEMBL5342716 0.94 BCHE (0.36) BCHECTSKCTSVCTSLCTSB
SCHEMBL5337364 0.94 BCHE (0.36) BCHECTSKCTSVCTSLCTSB
SCHEMBL5337554 0.94 BCHE (0.36) BCHECTSKCTSVCTSLCTSB
SCHEMBL5344263 0.94 BCHE (0.36) BCHECTSKCTSVCTSLCTSB
SCHEMBL5341496 0.94 BCHE (0.34) BCHECTSKCTSVCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6624306-B2 Stabilizer for addition polymer CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-23 US claimed
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2003-09-04 US claimed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 US claimed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 US disclosed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 US disclosed
US-7160966-B2 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-09 US disclosed
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides NESVADBA PETER (CH) 2005-06-30 US disclosed
US-6624306-B2 Stabilizer for addition polymer CIBA SPECIALTY CHEMICALS CORPORATION 2003-09-23 US disclosed
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides CIBA SPECIALTY CHEMICALS CORP. 2003-04-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030166939-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 BCHE 4189/4885FFAR1 389/4885CTSK 4787/4885
US-20050143539-A1 2,2,6,6 Diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 BCHE 4189/4885FFAR1 389/4885CTSK 4787/4885
US-20030065184-A1 2,2,6,6 diethyl-dimethyl-1-alkoxy-piperidine compounds and their corresponding 1-oxides ALKBH2, NFE2L2, DPYSL2 BCHE 4189/4885FFAR1 389/4885CTSK 4787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.