SCHEMBL534329

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21664123	0.77	ALDH1A1 (0.47)	HPGDUSP2MAPT
	SCHEMBL534104	0.72	CA1 (0.57)	CA1CA2CA9TP53TDP1
	SCHEMBL20946426	0.71	CA1 (0.77)	CA1CA2CA9CYP19A1CYP1A2
	SCHEMBL7507787	0.71	CA1 (0.71)	CA1CA2CA9CYP19A1CYP1A2
	SCHEMBL27950175	0.71	CA9 (0.71)	CA1CA2CA9TP53CYP19A1
	SCHEMBL6289448	0.71	CYP19A1 (0.78)	CA1CA2CA9CYP19A1CYP1A2
	SCHEMBL4663044	0.71	KEAP1 (0.76)	CA1CA2CA9CYP19A1CYP1A2
	SCHEMBL13972679	0.69	CA1 (0.68)	CA1CA2CA9CYP19A1CYP1A2
	SCHEMBL1893565	0.68	ALDH1A1 (0.76)	CA1CA2CA9TP53CYP19A1
	SCHEMBL1046937	0.68	CXCR4 (0.69)	CA1CA2CA9CYP19A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.